There are several great things about this image of my Dad and his two siblings, taken in 1956 at Nekoosa, Wisconsin. The colors from the Kodachrome slide film are vivid, from the blue sky to the slicked-back black hair. The clothes are natty and the hairstyles are so 1950s. Right to left are Donn Gene Hanneman (1926-2014), Lavonne (Hanneman) Wellman (1937-1986), and my Dad, David D. Hanneman (1933-2014).
The photo was taken at the home of the trio’s uncle and aunt, Marvin and Mabel Treutel. The occasion was a Treutel family reunion. Their mother and my grandmother, Ruby V. Hanneman (1904-1977), was a Treutel before marrying Grandpa Carl F. Hanneman (1901-1922). It’s sad to think all three of them are gone, but I find comfort in the hope they are together in Heaven.
The photograph is very poignant. A frail man, sitting in the afternoon sun on the front porch steps. He looks haggard and tired, maybe ill. This image is the last known photograph taken of Karl Frederick Christian Hanneman, who was known around Wisconsin Rapids as Charles or “Chas” Hanneman. The photo likely dates to 1931 or 1932, when he suffered from prostate cancer that eventually took his life.
Charles Hanneman came to America in late November 1882 with his parents, Christian and Amanda Hanneman. He was just 15 when the family made its way from Stettin, Pomerania to Portage County, Wisconsin. Charles, his three brothers and two sisters settled on a 105-acre farm in the northwest corner of the Town of Grant, near the tiny hamlet of Kellner.
Nina and Elaine Treutel visit with Chas Hanneman, circa 1930.
Charles worked on the Hanneman farm for a time. His brothers would stay in farming (maps from that period show many Hanneman farms in Portage County), but eventually Charles left farming and found work in one of the area’s many sawmills.
At some point in his early 20s, Charles made the acquaintance of Rosine Ostermann, the eldest daughter of John and Mina Ostermann of the Town of Grand Rapids. They had many things in common. Both grew up on the family farm. Rosie’s parents were from Germany (Saxony and Prussia), and his were from Pomerania. Rosie’s grandfather George Ostermann was one of the pioneers of Portage County, listed on the earliest tax roll of the Town of Grant in 1864.
On April 2, 1891, Charles and Rosie were married atSt. John’s Evangelical Lutheran Church in Kellner in a divine service performed by A.G. Grimm. The witnesses were Charles’ father, Christian, and his brother, William. The bride’s attendants were her sister, Elsie Ostermann, and Emma Pribbernow. The groomsmen were cousins August Saeger and Herman Hanneman.
The young couple came to know heartache early in their marriage. Their firstborn, referred in the records only as “C.H. Hanneman,” died in infancy in 1892. They went on to have four sons: Arthur John (1893), Frank Herman Albert (1895), Wilbert George (1899), and our own Carl Henry Frank (1901).
Left to right: Christian Hanneman, Chas Hanneman, Carl Hanneman, David D. Hanneman.
Work in the sawmill must have been erratic, or Charles left that occupation for a time. In 1900, U.S. Census records show the family living and working on the farm of Charles’ brother, William Hanneman.
By 1905, Charles moved his family to the second ward in the city of Grand Rapids. He initially did manual labor for the city of Grand Rapids,possibly working on construction of the water and sewer works. The financial statements for the city in December 1907 show Charles worked 135 hours that month and earned 17.5 cents per hourfor a paycheck of $23.63.
By 1910 the family was living at 1774 Baker Street in Grand Rapids. The U.S. Census that year lists Charles as a laborer at a box factory. That may have referred to Consolidated Water, Power & Paper Co., where he later worked until his retirement, or the nearby Badger Box company.
On March 31, 1918, tragedy struck the Hanneman home when Rosine died suddenly at age 48. Her death notice, which ran on page 1 of the Daily Leader, said she was fine during the day but fell ill and died at 11 p.m. We know that she had diabetes, and that may have contributed to her death. Carl was 16 when his mother died.
Charles remarried in August 1919 and lived out his remaining years in his home at 1751 Baker Street. He became ill with prostate cancer in 1931 and was hospitalized numerous times in Wausau for surgery and treatments. He died at home on Oct. 11, 1932. He was 65. His death made front-page news in the Wisconsin Rapids Daily Tribune.
FAMILY LINE: Karl Frederick Christian Hanneman >> Carl F. Hanneman >> Donn, David & Lavonne Hanneman
Rosine Bertha Henrietta (Osterman) Hanneman (1870-1918), Frank Herman Albert Hanneman (1895-1947), Arthur James Hanneman (1893-1965), Carl Henry Frank Hanneman (1901-1982), Wilbert George Hanneman (1899-1987) and Carl Frederick Christian (Chas) Hanneman (1866-1932).
It is the only known photograph showing six of the seven children of Christian and Amanda Hanneman, pioneers of Portage and Wood counties in Wisconsin. The undated photo was probably taken around 1915 at a family event. Left to right are: William Friedrich Johann Hanneman (1856-1939) Bertha Auguste Ernestine (Hanneman) Bartelt (1860-1945) Albert Friedrich O. Hanneman (1863-1932) Herman Charles Hanneman (1864-1945) Carl Friedrich Christian Hanneman (“Chas,” 1866-1932) Ernestine Wilhelmine Caroline (Hanneman) Timm (1870-1930)
Hand tinted photograph of Chas Hanneman, location unknown.
Left to right: Christian Hanneman, Chas Hanneman, Carl Hanneman, David D. Hanneman.
Just three weeks after becoming a father for the third time, young pharmacist Carl. F. Hanneman took the extraordinary step of writing to the attorney general of Wisconsin to ask that he be granted full licensure as a registered pharmacist. It was a heartfelt letter, written by a young man feeling the weight of responsibility of a wife and three children. Written by a well-educated and accomplished man who felt he deserved what he as asking. The very future was at stake.
“I am writing this letter in all sincerity as what I am about to ask means everything to myself as well as my wife and three little kiddies,” Carl wrote to Attorney Gen. Orland S. Loomis on Sept. 3, 1937.“I am 35 years old and will be 36 this coming October and feel that obtaining my full registered papers will mean life itself to myself and my dear family.”
Carl explained that he was fully licensed as an assistant pharmacist, working at the Mauston Drug Store owned by Dr. J.S. Hess Jr. But he was unable to officially manage the drug store due to a quirk in state law.
Wisconsin Attorney Gen. Orland S. Loomis of Mauston
If Carl had worked in a smaller town with under 500 population, he could have legally managed the pharmacy. But Mauston population was about 2,100. Carl would need to be a registered pharmacist in order to manage the Mauston Drug Store.
“My capacity in the drug store is as an unofficial manager, as I do all of the buying etc., but legally cannot manage the store,” Carl wrote. “Dr. J.S. Hess Jr. has confidence in me and I a great deal in him, and as far as I am concerned am willing to stay here the rest of my life, dispensing for our own doctors.”
Carl reasoned that if he was qualified to own and manage a pharmacy in a small town (such as neighboring Lyndon Station, pop. 236), why could he not serve the same capacity in Mauston? “I have often wondered as has many others, are not the lives of 500 people in a small town just as valuable to their loved ones as those living in a town where there might be more than this amount?” Carl wrote.
A label under glass from Carl F. Hanneman’s pharmacy collection.
By 1937, Carl had 16 years of experience in pharmacology, starting as an apprentice in 1921 at the Sam Church drug store in Wisconsin Rapids. Carl graduated from the pharmacy program at Marquette University in 1925 and became licensed as an assistant pharmacist. He wasn’t eligible to take the full pharmacist exam at the time because his apprenticeship fell just short of the required five years. Over the next decade he worked at drug stores in Janesville, Fond du Lac and Wisconsin Rapids, and even worked a three-year stint as a salesman for Consolidated Water Power & Paper Co.
“I knew my lifework was with the drug store as I truly love it and was very fortunate in securing a position with the Dr. Hess Hospital, Clinic and Drug Store organization on Feb. 1, 1936,” Carl wrote.
Carl said he would likely need three more years of study to pass the registered pharmacist board exams as they existed in 1937. With three children (including baby Lavonne born in August 1937), Carl figured that simply would not be possible. So he asked for help from Loomis, a Mauston native who served as city attorney from 1922 to 1931. Loomis was attorney general through 1938, and was elected governor of Wisconsin in 1942. He died before taking office. Eventually, Carl became good friends with Loomis and photographed him for the Wisconsin State Journal on the 1942 night of his election as governor of Wisconsin.
Carl F. Hanneman’s registered pharmacist license, issued in July 1944.
We don’t know if Loomis ever intervened on Carl’s behalf in his role as attorney general or governor-elect, or how he responded to the 1937 letter. A search of Loomis’ law-practice records at the Wisconsin Historical Society yielded no clues. Carl’s 1941 license from the Wisconsin State Board of Pharmacy still lists him as an assistant pharmacist. On July 12, 1944, the state of Wisconsin issued an ornate document certifying Carl as a full registered pharmacist. He worked under the new license number until his death in 1982. It would appear Carl secured his added credentials the hard way: he earned them.
Nothing was bigger news in the fall of 1950 in central Wisconsin than Mary Ann Van Hoof and her claims of receiving visions from the Blessed Virgin Mary at the Van Hoof farm near Necedah. Members of the Hanneman family of Mauston, had great devotion to Mary, and they were among 50,000 people in Necedah on October 7, 1950, when Van Hoof received the eighth of her reported visions of Mary.
The front page of the Wisconsin State Journalthe next day recounted the alleged vision this way:
Mary Ann Van Hoof at her farm near Necedah, Wisconsin.
“Mrs. Fred Van Hoof said she saw the Virgin Mary in a vision for the eighth time Saturday and was told in a ‘last warning’ to pray for peace. The gaunt farm wife, who said last August that the Virgin would appear to her Saturday noon in a blinding light, walked from her shabby home at the appointed hour, knelt in prayer and raised a crucifix to a statue of the Virgin. At that moment, the sun burst through rain clouds which had hovered over the humble farm most of the morning, and a murmur swept through the crowd estimated by state police at 50,000 persons.After a few minutes, Mrs. Van Hoof arose and addressed the mingled throng of curious and claims to have done on previous visitations. ‘This is the battle for peace for all of you,’ she said. ‘Prayer, my dear children, will bring you peace.’ ”
Rev. Father Victor A. Fortino
A priest from Watervliet, Michigan, who was also in attendance that day befriended the Hanneman family. Rev. Father Victor A. Fortino of St. Joseph’s Church in Watervliet, cautioned 17-year-old David D. Hanneman to wait for Catholic Church authorities to approve the alleged visions before he placed too much stock in them. “I hope that what transpired at Necedah will receive the approval of the Church authorities,for without it, we simply cannot believe Mrs. Van Hoof’s claims even though you and I enjoyed the same experience during the alleged apparition of Oct. 7,” Fortino wrote in a letter dated October 27, 1950.
The Van Hoof farm near Necedah, Wisconsin, was the site of reported visions of the Blessed Virgin Mary.
Father Fortino warned that Satan has appeared to Saints and sinners alike posing as the Blessed Mother and as the Crucified Christ, so it is crucial that the Church rule on the Van Hoof apparitions. “I want to warn you about something,” Fortino wrote. “DO NOT AS YET ACCEPT THE NECEDAH STORY AS TRUE. WAIT UNTIL THE ECCLESIASTICAL AUTHORITIES HAVE DECIDED ON THE CASE.”
As it turned out, Fortino’s words were almost prophetic. In June 1955, Bishop John Treacy of the Diocese of La Crosse officially rejected Van Hoof’s visions.“Because of the continued promotion of the claims made by Mrs. Mary A. Van Hoof of Necedah, Wis., we, by virtue of our authority as bishop of the diocese of La Crosse, hereby declare that all claims regarding supernatural revelations and visions made by the aforementioned Mrs. Van Hoof are false. Further more, all public and private religious worship connected with these false claims is prohibited at Necedah, Wis.” As early as August 1950, Bishop Treacy had said Van Hoof’s claims “are of extremely doubtful nature.”
Father Victor Fortino urged David Hanneman: “be very careful.”
Father Fortino may have suspected the Necedah claims would turn out to be false, but he wrote that some good could come from the gathering that week in 1950 no matter what. “It seemed to me that Our Lady brought us together for Her own good purposes,” Fortino wrote. “What She intends for us, I do not know. But I hope that much good will come out of our chance meeting and our mutual experience in Necedah.”
Despite the controversy over Van Hoof and her claims, the Hanneman family maintained strong devotion to the Blessed Virgin Mary. Carl and Ruby Hanneman kept a beautiful porcelain statue of the Blessed Mother in their Mauston home. After their deaths that statue found a place at David Hanneman’s residence in Sun Prairie. And it sat in front of the altar at his funeral Mass on April 19, 2007.
My Dad’s family made several trips out West, to Arizona and the Dakotas. Sorting out and matching photos with cities has been a constant challenge. A couple of intriguing photos show Dad with a cowboy identified as Hiram Greene. I wondered, was Hiram Greene a famous rodeo rider, a film star or some other celebrity?
My first source of information was the caption on the back of one photo, written by my grandmother, Ruby V. Hanneman. It listed the name “Hiram Greene” and said he was from Billings, Montana. The photo, according to the caption, was taken at Canistota, Minnesota. As it turned out, that caption was problematic in several respects.
Hiram Greene with David D. Hanneman on July 14, 1945.
I took a chance by doing a generic search engine query and came up empty. I quickly ruled out the idea that Mr. Greene was a major celebrity. Using databases at Ancestry.com, I was unable to find anyone by that name near Billings, Montana. But I did find what appeared to be a good match right in South Dakota, where the Hanneman family vacationed several times in the 1940s.
Hiram Hoyt Greene was a farmer who lived much of his life around Mitchell, S.D. I ran a quick search and discovered the major tourist attraction in Mitchell is the Mitchell Corn Palace, home to world-famous murals made from corn. That quickly rang a bell with me. I had numerous photos of the Hannemans outside the Corn Palace. This led me to conclude that it was possible that Dad met Hiram Greene on the streets of Mitchell. Especially since there is no Canistota, Minnesota. There is a Canistota, S.D., another city the Hanneman family visited on vacation. Canistota is home to the famous Ortman Chiropractic Clinic. I could find no link between Hiram and Canistota, although it is only 40 miles from Mitchell. I took yet another look through the photo library and found an image of the Ortman Clinic. The building next to it appears to match the brick building that Dad and Mr. Greene are standing near. So it was Canistota after all.
According to the 1940 U.S. Census, Hiram Hoyt Greene was a livestock and grain producer. This made sense. A cattle rancher would certainly dress like a cowboy. Perhaps Dad saw Mr. Greene on the street and wanted to have his photo taken with a real cowboy. I wonder if that had happened to Mr. Greene before? I started out looking for a celebrity, but found a regular, hard-working cattle rancher. It was an even better story, in my opinion.
Hiram Hoyt Greene was born in May 1898. At the time of the World War I draft, he was a farmer in Mitchell, S.D. In May 1920, he married May Luella Moe. The couple had nine children. At various times in his working life, Greene farmed and lived in Mitchell, the Town of Beulah and Mount Vernon, South Dakota. He was hospitalized in November 1958, just a day after celebrating the wedding of one of his sons. He died on November 28, 1958 at age 60.
I learned several key lessons from this photo detective assignment. First, it is always a good idea to write down information on the back of photographs. Or in the case of modern digital images, to embed a caption and keywords in the photo files. But you can’t always trust the information on old photo prints. Sometimes captions are written long after the events shown in the photo. Memories can be jumbled, so it is good to check the information and correct it if necessary.
— This post has been updated with more information.
[The original version of this story posted in 2014 stated that President Truman visited Mauston, Wisconsin. A sharp-eyed former resident of Mauston noted in the comments section that Truman did not visit Mauston, but rather nearby Elroy. The Truman Presidential Library has now confirmed this, so the story has been corrected and expanded as of May 10, 2017.]
When President Harry S Truman pulled into tiny Elroy, Wisconsin on his rail tour of America in 1948, the Carl F. Hanneman family was at the station and captured several Polaroid images of the event. The grainy and out of focus photos are far from perfect, but they provide literal snapshots from one of the great political stories in American history.
The Harry S Truman express approaches Elroy, Wisconsin, on October 14, 1948.
Truman went on an 30,000-mile“whistle-stop” railroad tour of the nation,visiting large cities, small villages and everything in between. His 17-car train was called the Magellan. Much like his old boss President Franklin Delano Roosevelt had done, Truman made speeches from a presidential podium at the back of the train. The tour drew huge crowds wherever he went, and Mauston was no exception. According to the Truman Presidential Library, the president made up to eight speeches each day during the rail tour.
President Harry S Truman took his case directly to the people during his 1948 rail tour.
On this day, Truman started out with a speech in Mankato, Minnesota at 8:08 a.m. Other stops included Waseca, Rochester and Winona, Minnesota; and Sparta, Wisconsin. The train pulled into Elroy at 1:55 p.m. on October 14, 1948. Truman stepped to the podium and said:
I certainly do appreciate your coming out here. This was supposed to have been a water stop. I didn’t think that we would be here long enough for me to speak to you, but I am happy that we did stop long enough, and I appreciate your interest and I appreciate your coming out here to see the president.
I wish I had the chance to discuss with you all the issues in this campaign, but I haven’t the time now.
I hope you’ve been reading the speeches and statements I have been making over the country. They are in your interest, and if you vote for your own interests on the 2d of November you’ll elect a Democratic Governor and a Democratic Congressman from your district–and you’ll elect a Democratic administration in the whole United States Government. And then things will be safe and in the hands of the people.
Conventional political wisdom had Truman losing badly before a single ballot was cast. When he won the election, it was viewed as a stunning turn of events. Many will recall the famous photo of Truman holding the early edition of the Chicago Tribune with the erroneous headline, “Dewey Defeats Truman.” That photo was snapped at the back of the same train in St. Louis, as Truman departed for Washington.
It seems the term “whistle-stop” was considered a bit of a slight. When Republican Sen. Robert Taft of Ohio criticized the Democrat Truman for things he was saying on the “whistle-stop” tour, mayors of towns on the route of Truman’s tour reacted with indignation. “Our whistles never stop blowing,” one huffed. Crestline, Ohio, was quick to point out the 42 daily trains that served its population of 5,000. The Associated Press at the time said a whistle-stop was a “tank town, a hamlet, a mere wide place in the road.” Truman’s own comments at Elroy indicate the stop there was supposed to be only to take on water.
Of course millions of Americans live in such places, so the kerfuffle seemed a bit strange. As columnist Thomas L. Stokes noted, “Whistle-stop folks vote, too.” Stokes called the rail tour a public service, part of a president’s responsibility to communicate directly with the American people.
Esther Marie Albrecht was married to Emil Rudolph Gottschalk on November 12, 1930 in the Town of Hewitt in Wood County, Wisconsin. Esther was the maid of honor at the July 1925 wedding of Ruby V. Treutel and Carl F. Hanneman in Vesper, Wisconsin. Mr. and Mrs. Gottschalk moved to Waukesha, and had two daughters, Pearl and LaVon. They were longtime friends of the Hanneman family. She is the daughter of George and Pearl (Smith) Albrecht.
Esther M. Albrecht married Emil R. Gottschalk in November 1930 in the Town of Hewitt, Wood County, Wisconsin.
According to the 1930 and 1940 U.S. Census, Emil worked as a core maker in an iron foundry in Waukesha. Emil Gottschalk died on February 1, 1944 at just age 37. Mrs. Gottschalk operated Esther’s Food Store on Arcadian Avenue in Waukesha. In April 1946, she married Harold D. “Whitey” Buchs at St. Joseph’s Catholic Church in Waukesha. Esther died January 1, 1985 in Vesper. Harold died April 13, 2007 in Vesper.
Stevie Wilson and Laurni Lee Wilson made their own Christmas greeting in December 1942 with this photograph sent to their Uncle and Aunt, Carl and Ruby Hanneman of Mauston, Wisconsin. They even included greetings from their dog, Melissa. The Wilsons lived in Waukegan, Illinois, where the Hanneman family often visited. Stevie and Laurni Lee are the children of Lawrence and Nina (Treutel) Wilson. Nina is Ruby (Treutel) Hanneman’s sister. Merry Christmas!
We only have two photographs that show Carl F. Hanneman at school, and both appear to be from the same year. In the first, Carl is the second pupil in the second row at a school in Grand Rapids, Wisconsin. Wearing a tie and cardigan sweater, Carl is one of a half-dozen or so boys in the class. The clock reads 11:59, so the class photo was scheduled just before the lunch break. It is a well-kept and neatly appointed classroom. The girl sitting in front of Carl could easily be mistaken for his future bride, Ruby V. Treutel, although she went to school in nearby Vesper.
Carl F. Hanneman is third from the left in the first row. The photo was taken circa 1910.
The second photo was taken outdoors at an entrance to the school. Carl is third from the left in the first row. At the time, the Hannemans lived on Baker Street in Grand Rapids, so the Howe School would have been the closest public school. But the building in the photo does not match exterior details of the Howe School, so it’s unclear where Carl spent his elementary school years.
During his nearly six decades as a pharmacist, Carl F. Hanneman got to know a lot of people. He forged good relationships with the many sales reps who called on him at the Mauston Drug Store. Some came to dinner at the Hanneman home, and a few even stayed at the house while in town. One of the long-lasting perks he received from Parke, Davis and Company was a stunning set of lithographs depicting the history of pharmacy. More than 30 prints still exist from Carl’s 1950s collection.
Parke-Davis commissioned artist Robert Thom to produce 40 illustrations for the series, “A History of Pharmacy in Pictures.” Each print came with a history article that explained the depicted scene and its place in history. Launched in 1957, the series was developed in cooperation with the Institute for the History of Pharmacy at the University of Wisconsin. Druggists were encouraged to display the artwork in their stores.
The series depicted such early topics as scientist Galen in the second century to later developments such as chemotherapy, antibiotics and pharmaceutical research. Parke Davis also commissioned Thom to paint a series of illustrations on the history of medicine. Thom (1915-1979) was well known as an illustrator of historical subjects, including great moments in baseball and the history of Illinois and Michigan.
The paintings from Carl Hanneman’s collection are in the gallery below, including the explanatory text from each image.
— This post has been updated with additional Thom paintings.
Man learned early of the prestigious advantage of trademarks as a means of identification of source and of gaining customers’ confidence. One of the first therapeutic agents to bear such a mark was Terra Sigillata (Sealed Earth), a clay tablet originating on the Mediterranean island of Lemnos before 500 B.C. One day each year clay was dug from a pit on a Lemnian hillside in the presence of governmental and religious dignitaries. Washed, refined, rolled to a mass of proper thickness, the clay was formed into pastilles and impressed with an official seal by priestesses, then sun-dried. The tablets were then widely distributed commercially.
In the evolution of all successful and enduring systems of knowledge there comes a time when the observations of many men, or the intensive studies of one, transcend from the level of trade or vocation to that of a science. Pedanios Dioscorides (first century A.D.), contributed mightily to such a transition in Pharmacy. In order to study materia medica, Dioscorides accompanied the Roman armies throughout the known world. He recorded what he observed, promulgated excellent rules for collection of drugs, their storage and use. His texts were considered basic science as late as the sixteenth century.
Of the men of ancient times whose names are known and revered among both the professions of Pharmacy and Medicine, Galen, undoubtedly, is the foremost. Galen (130-200 A.D.) practiced and taught both Pharmacy and Medicine in Rome; his principles of preparing and compounding medicines ruled in the Western world for 1,500 years; and his name still is associated with that class of pharmaceuticals compounded by mechanical means – galenicals. He was the originator of the formula for a cold cream, essentially similar to that known today. Many procedures Galen originated have their counterparts in today’s modern compounding laboratories.
Twinship of the health professions, Pharmacy and Medicine, is nowhere more strikingly portrayed than by Damian, the apothecary, and Cosmas, the physician. Twin brothers of Arabian descent, and devout Christians, they offered the solace of religion as well as the benefit of their knowledge to the sick who visited them. Their twin careers were cut short in the year 303 by martyrdom. For centuries their tomb in the Syrian city of Cyprus was a shrine. Churches were built in their honor in Rome and other cities. After canonization, they became the patron saints of Pharmacy and Medicine, and many miracles were attributed to them.
During the Middle Ages remnants of the Western knowledge of Pharmacy and Medicine were preserved in the monasteries (fifth to twelfth centuries). These scientists are known to have been taught in the cloisters as early as the seventh century. Manuscripts from many islands were translated or copied for monastery libraries. The monks gathered herbs and simples in the field, or raised them in their own herb gardens. These they prepared according to the art of the apothecary for the benefit of the sick and injured. Gardens such as these still may be found in monasteries in many countries.
The Arabs separated the arts of apothecary and physician, establishing in Bagdad late in the eighth century the first privately owned drug stores. They preserved much of the Greco-Roman wisdom, added to it, developing with the aid of their natural resources syrups, confections, conserves, distilled waters and alcoholic liquids. The apothecary is examining logs of sandalwood offered by a traveling merchant, while children indulge their taste for sweets with stalks of sugar cane. When the Moslems swept across Africa, Spain and southern France, they carried with them a new pattern of Pharmacy which western Europe soon assimilated.
Among the brilliant contributors to the sciences of Pharmacy and Medicine during the Arabian era was one genius who seems to stand for his time – the Persian, Ibn Sina (about 980-1037 A.D.), called Avicenna by the Western world. Pharmacist, poet, physician, philosopher and diplomat, Avicenna was an intellectual giant, a favorite of Persian princes and rulers. He wrote in Arabic, often while secluded in the home of an apothecary friend. His pharmaceutical teachings were accepted as authority in the West until the 17th century; and still are dominant influences in the Orient.
In European countries exposed to Arabian influence, public pharmacies began to appear in the 17th century. However, it was not until about 1240 A.D. that, in Sicily and southern Italy, Pharmacy was separated from Medicine. Frederick II of Hohenstaufen, who was Emperor of Germany as well as King of Sicily, was a living link between Oriental and Occidental worlds. At his palace in Palermo, he presented subject Pharmacists with the first European edict completely separating their responsibilities from those of Medicine, and prescribing regulations for their professional practice.
The idea of a pharmacopoeia with official status, to be followed by all apothecaries, originated in Florence. The Nuovo Receptario, originally written in Italian, was published and became the legal standard for the city-state in 1498. It was the result of collaboration of the Guild of Apothecaries and the Medical Society – one of the earliest manifestations of constructive interprofessional relations. The professional groups received official advice and guidance from the powerful Dominican monk, Savonarola, (seated, foreground) who, at the time, was the political leader in Florence.
Trade in drugs and spices was lucrative in the Middle Ages. In the British Isles, it was monopolized by the Guild of Grocers, which had jurisdiction over the apothecaries. After years of effort, the apothecaries found allies among court physicians. King James I, flanked by two “Beefeaters” wore heavily padded attire because of fear of stabbing. Upon persuasion by the philosopher-politician, Francis Bacon, the King granted a charter in 1617 which formed a separate company known as the “Master, Wardens and Society of the Art and Mystery of the Apothecaries of the City of London” over vigorous protests of the grocers. This was the first organization of pharmacists in the Anglo-Saxon world.
Young Parisian Apothecary Louis Hébert answered the call of the New World in 1605, when he helped de Monts and Champlain build New France’s first settlement, the Habitation, at Port Royal (Nova Scotia, Canada). Hébert looked after the health of the pioneers, cultivated native drug plants, and supervised the gardens. At the waterfront, he examined specimens of drug plants offered by Micmac Indians. These included Arum, (Jack-in-the-Pulpit), Eupatorium (Boneset), Verbascum (Mullein), and Hydrastis (Golden Seal). When the Habitation was destroyed by the English in 1613, he returned to his Parisian apothecary shop. The lure of Canada was strong, however, and in 1617, he and the family returned with Champlain to Quebec, where Hébert’s “green thumb” gained him lasting fame as the first successful farmer in what is now Canada.
Many Europeans “of quality and wealth, particularly those who were non-conformists in religion” were attracted to the possibilities of the American Colonies. From Britain came John Winthrop, first Governor of Massachusetts Bay Colony and founder of Boston. Governor Winthrop, unable to induce professionals to the Colony, sought advice from English apothecaries and physicians, and added to his small store of imported drugs those derived from plants native to New England. In his home (about 1640), he made available as best he could the “art and mystery” of the apothecary for his citizens.
Christopher Marshall, an Irish immigrant, established his apothecary shop in Philadelphia in 1729. During 96 years, this pioneer pharmaceutical enterprise became a leading retail store, nucleus of large-scale chemical manufacturing; a “practical” training school for pharmacists; an important supply depot during the Revolution; and finally, it was managed by granddaughter Elizabeth, America’s first woman pharmacist. Christopher earned the title of “The fighting Quaker” during the Revolution; his sons, Charles and Christopher, Jr., (shown as youths with their father, about 1754) earned individual fame and carried on his fine traditions.
Colonial America’s first hospital (Pennsylvania) was established in Philadelphia in 1751; the first Hospital Pharmacy began operations there in 1752, temporarily set up in the Kinsey house, which served until the first hospital building was completed. The ingenuity of Benjamin Franklin was helpful in both. First Hospital Pharmacist was Jonathan Roberts; but it was his successor, John Morgan, whose practice as a hospital pharmacist (1755-56), and whose impact upon Pharmacy and Medicine influenced changes that were to become of importance to the development of professional pharmacy in North America. First as pharmacist, later as physician, he advocated prescription writing and championed independent practice of two professions.
During his few short years, Carl Wilhelm Scheele gave to the world discoveries that have brought its people incalculable advantages. Yet he never forgot that he was, first of all, a pharmacist. Encouraged by enlightened preceptors, all of his discoveries were made in the Swedish pharmacists in which he worked, as apprentice, as clerk, and finally as owner, in Köping. He began in a corner of the stock room of Unicorn Apothecary in Gothenburg. With rare genius, he made thousands of experiments, discovered oxygen, chlorine, prussic acid, tartaric acid, tungsten, molybdenum, glycerin, nitroglycerin, and countless other organic compounds that enter into today’s daily life, industry, health, and comfort.
The first man to hold the rank of a commissioned pharmaceutical officer in an American army was the Bostonian apothecary, Andrew Craigie. His duties included procurement, storage, manufacture and distribution of the Army’s drug requirements. He also developed an early wholesaling and manufacturing business.
Swedish pharmacist Scheele paved the way for isolating organic plant acids; but it remained for a young German apothecary, Friedrich Wilhelm Adam Sertürner, to give the world opium’s chief narcotic principle, morphine; and to recognize and prove the importance of a new class of organic substances: alkaloids. His first announcements challenged, Sertürner in 1816 conducted a new series of bold, startling experiments in his apothecary shop in Einbeck, including a series of physiologic tests on himself and three young friends. Recognition and fame followed. Relocating in an apothecary shop in Hameln, Sertürner continued organic chemical experimentation and discovery throughout his life.
Taking their cue from Sertürner’s alkaloidal experiments, two French pharmacists, Messrs. Pierre-Joseph Pelletier and Joseph-Bienaimé Caventou, isolated emetine from ipecacuanha in 1817; strychnine and brucine from nux vomica in 1818; then, in their laboratory in the back of a Parisian apothecary shop, they tackled the problem that had baffled scientists for decades – wresting the secrets of the Peruvian barks that were so useful against malaria. In 1820 Caventou and Pelletier announced the methods for separation of quinine and cinchonine from the cinchona barks; prepared pure salts, had them tested clinically, and set up manufacturing facilities. Many other discoveries came from their pharmacy-laboratory; high honors were accorded them.
Faced with two major threats; deterioration of the practice of pharmacy, and a discriminatory classification by the University of Pennsylvania medical faculty, the pharmacists of Philadelphia held a tempestuous protest meeting in Carpenters’ Hall, February 23, 1821. At a second meeting, March 13, the pharmacists voted formation of: an association, which became The Philadelphia College of Pharmacy; a school of pharmacy; and a self-policing board. Sixty- eight pharmacists signed the Constitution of the first pharmaceutical association in the United States; American Pharmacy’s first educational institution, bearing the same name, opened November 9.
First U.S. industry in medicinal herbs was carried on by the United Society of Believers in Christ’s Second Appearing, commonly known as the Shakers. Begun about 1820, and commercially important by 1830, the medicinal herb industry grew, hit its peak in the 1860’s, then waned at the close of the century. The Shakers gathered or cultivated some 200 varieties; dried, chopped, and pressed them into “bricks”; wrapped, labeled, and sold them to pharmacists and physicians world-wide. Tons of solid and fluid extracts also were produced. The Shaker label was recognized for reliability and quality for more than a century.
Need for better intercommunication among pharmacists; standards for education and apprenticeship; and quality control of imported drugs, led to calling of a convention of representative pharmacists in the Hall of the Philadelphia College of Pharmacy, October 6 to 8, 1852. Under leadership of its first President, Daniel B. Smith, and first Secretary, William Procter, Jr., the twenty delegates launched The American Pharmaceutical Association; mapped its objectives; and opened membership to “All pharmaceutists and druggists” of good character who subscribed to its Constitution and to its Code of Ethics. The Association continues to serve Pharmacy today.
Over the years, no real discord has existed between representatives of European and American Pharmacy so far as ethical and scientific aims are concerned. But when the groups met for the first time, at the Second International Congress of Pharmacy in Paris, France, August 21 to 24, 1867, there was a great divergence of opinion on the subject of compulsory limitation of pharmacies. William Procter, Jr., leading the delegates of The American Pharmaceutical Association, told the international body that “Public opinion is in America a forceful agent of reform,” and that, in his country, “there is not the slightest obstacle toward a multiplication of drug stores save that a lack of success.” His declaration vividly documented the American Way of Pharmacy.
Rarely has a titular distinction been so deserved. William Procter, Jr., graduated from The Philadelphia College of Pharmacy in 1837; operated a retail pharmacy; served the College as Professor of Pharmacy for 20 years; was a leader in founding The American Pharmaceutical Association; served that organization as its first secretary; later, as its president; served 30 years on the U.S.P. Revision Committee; was for 22 years Editor of the American Journal of Pharmacy. In 1869, though retired, Procter continued to edit the Journal in a small publication office located beside the College’s Tenth Street building. From retirement he returned to P.C.P.’s chair of Pharmacy in1872; literally died “in the harness,” in 1874.
When Dr. Albert B. Prescott launched the pharmacy course at the University of Michigan in 1868, critical attention was aroused because he abandoned the traditional requirement of pregraduation apprenticeship. At the 1871 convention of the American Pharmaceutical Association, he was denied credentials and ostracized. However, the Michigan course pioneered other major changes: laboratory pharmacy, a definite curriculum that included basic sciences, and a program that demanded students’ full-time attention. During the next thirty years, Dr. Prescott had the satisfaction of seeing his once revolutionary innovations generally adopted by pharmaceutical faculties.
The first “United States Pharmacopoeia” (1820) was the work of the medical profession. It was the first book of drug standards from a professional source to have achieved a nation’s acceptance. In 1877, the “U.S.P.” was in danger of dissolution due to the lack of interest of the medical profession. Dr. Edward R. Squibb, manufacturing pharmacist as well as physician, took the problem to The American Pharmaceutical Association convention. Pharmacists formed a “Committee on Revision” chairmanned by hospital pharmacist Charles Rice, assisted by pharmacist-educator Joseph P. Remington, and by Dr. Squibb, their indefatigable collaborator. The “U.S. Pharmacopoeia” surged to new importance.
Despite the professional skill and integrity of 19th-century pharmacists, seldom did two preparations of vegetable drugs have the same strength, even though prepared by identical processes. Plant drugs varied widely in active alkaloidal and glucosidal content. The first answer to this problem came when Parke, Davis & Company introduced standardized “Liquor Ergotae Purificatus” in 1879. Dr. Albert Brown Lyons, as the firm’s Chief Chemist, further developed methods of alkaloidal assay. Messrs. Parke and Davis recognized the value of his work, and in 1883, announced a list of twenty standardized “normal liquids.” Parke-Davis also pioneered in developing pharmacologic and physiologic standards for pharmaceuticals.
Scientific explorers opened vast new horizons for Pharmacy late in the 19th century. Sent in 1885 to Peru, Dr. Henry H. Rusby crossed South America amid incredible hardships. He returned with 45,000 botanical specimens, including Cocillana Bark.
The French retail pharmacist, Stanislas Limousin, introduced many devices to Pharmacy and Medicine. His greatest contributions were invention of glass ampoules, the medicine dropper, and apparatus for inhalation of oxygen.
Biological products (made from micro-organisms) got their discovery of diphtheria antitoxin by the German, Behring, in 1894. Pharmaceutical manufacturers since have constantly improved serums, antitoxins and vaccines, which have saved countless lives.
One of the successful researchers in the development of new chemical compounds specifically created to fight disease-causing organisms in the body was the French pharmacist, Ernest Francois Auguste Fourneau (1872-1949), who for 30 years headed chemical laboratories in the world-renowned Institut Pasteur, in Paris. His early work with bismuth and arsenic compounds advanced the treatment of syphilis. He broke the German secret of a specific for sleeping sickness; paved the way for the life-saving sulfonamide compounds; and from his laboratories came the first group of chemicals having recognized antihistaminic properties. His work led other investigators to broad fields of chemotherapeutic research.
Research in some form has gone hand in hand with the development of Pharmacy through the ages. However, it was the chemical synthesis of antipyrine in 1883 that gave impetus and inspiration for intensive search for therapeutically useful compounds. Begun by the Germans, who dominate the field until World War I, the lead in pharmaceutical research passed thereafter to the United States. Research in Pharmacy came into its own in the late 1930’s and early 1940’s; has grown steadily since, supported by pharmaceutical manufactures, universities, and government. Today it used techniques and trained personnel from every branch of science in the unending search for new life-saving and life-giving drug products.
Pharmaceutical manufacturing as an industry apart from retail Pharmacy had its beginnings about 1600; really got under way in the middle 1700’s. It developed first in Germany, then in England and in France. In America, it was the child of wars – born in the Revolution; grew rapidly during and following the Civil War; became independent of Europe during World War I; came of age during and following World War II. Utilizing latest technical advances from every branch of science, manufacturing Pharmacy economically develops and produces the latest and greatest in drugs in immense quantities, so that everywhere physicians may prescribe them and pharmacists dispense them for the benefit of all mankind.
Antibiotics are not new. Their actions probably were first observed by Pasteur in 1877. However, the second quarter of the 20th century marked the flowering of the antibiotic era – a new and dramatic departure in the production of disease-fighting drugs. Fleming’s discovery of penicillin in 1929 went undeveloped and Florey and Chain studied it in 1940. Under pressure of World War II, the pharmaceutical manufacturers rapidly adapted mass production methods to penicillin; have reduced costs to 1/1000th the original. Antibiotic discoveries came rapidly in the ’40’s. Intensive research continues to find antibiotics that will conquer more of men’s microbial enemies.
Pharmacy, with its heritage of 50 centuries of service to mankind, has come to be recognized as of the great professions. Like Medicine, it has come through many revolutions, has learned many things, has had to discard many of its older ways. Pharmacists are among the community’s finest educated people. When today’s retail pharmacist fills a prescription written by a physician, he provides a professional service incorporating the benefits of the work of pharmacists in all branches of the profession – education, research, development, standards, production, and distribution. Pharmacy’s professional stature will continue to grow in the future as this great heritage and tradition of service is passed on from preceptor to apprentice, from teacher to student, from father to son.