Christopher Marshall, an Irish immigrant, established his apothecary shop in Philadelphia in 1729. During 96 years, this pioneer pharmaceutical enterprise became a leading retail store, nucleus of large-scale chemical manufacturing; a “practical” training school for pharmacists; an important supply depot during the Revolution; and finally, it was managed by granddaughter Elizabeth, America’s first woman pharmacist. Christopher earned the title of “The fighting Quaker” during the Revolution; his sons, Charles and Christopher, Jr., (shown as youths with their father, about 1754) earned individual fame and carried on his fine traditions.